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Old 12-22-2015, 02:39 AM   #1
Junior Member
Location: Shenzhen

Join Date: Aug 2010
Posts: 3
Default snp calling by Pacbio reads

Hi guys,

Glad to find this place.

Now I'm trying to use 50X pacbio reads for human genome re-sequencing analysis, like snp calling. However, multiple studies have shown that pacbio reads contain about 15% sequence errors, of which most are insertions.

In this case, I'm wondering if it is possible that we use pacbio reads only to do self-error correction (no illumina reads), and then find highly accurate snps?

Forgive my poor English level and thanks for your help.^_^
sunyuhui is offline   Reply With Quote

error correction, pacbio, re-sequencing

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