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Old 02-03-2010, 10:25 AM   #1
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Location: Malaysia

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Default Fragment Library vs Mate-pair library

The SOLid system allows the research 2 choices for sample preparation, the fragment library or mate-pair library in which fragment library involve single fragment DNA while mate-pair library involve two fragments of DNA.

Why is that need this two different sample preparation method?

What kind of situation we use these different method?
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Old 02-03-2010, 07:50 PM   #2
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mate-pair : structural variation, regions of large repeats or mutations, indels, unique coverage, complex genome snp discovery
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