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Old 10-03-2011, 05:42 PM   #1
elisadouzi
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Default which statistic method to use for DESeq

I'm comparing the DEG between two very similar sample. They are just come from same plant but selfing independently 10 years. Which statistic method is appropriate for DESeq?

Thanks a lot!
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Old 10-04-2011, 12:28 AM   #2
NicoBxl
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DESeq is a statistic method based on a non-binomial distribution. You've to used the raw reads as input. The best is to read the Simon Anders's paper on it : http://dx.doi.org/10.1186/gb-2010-11-10-r106

and the package doc : http://bioconductor.org/packages/rel...tml/DESeq.html
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Old 10-04-2011, 09:31 AM   #3
elisadouzi
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Thanks for the reply
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