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Old 09-23-2013, 09:03 AM   #1
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Location: Michigan

Join Date: Sep 2013
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Question Enrichment analysis with DAVID tool - question

Hi All,

I am still new in the field and I have a question please.

I have a dataset of gene expressions and I am running biclustering methods over them. The dataset is colon cancer dataset, When I get the new biclusters I want to do biological validation; enrichment analysis to find how many genes are enriched in each bicluster. I want to use DAVID tool for that.
My question is when I upload my gene set to DAVID tool, I choose "Functional Annotation Clustering" then I have set of clusters for the set of genes that I uploaded with different gene enrichment score. How can I find "Proportion of biclusters significantly enriched" as it has been done in Figure 3 of this paper "A systematic comparison and evaluation of biclustering methods
for gene expression data"

Any help please? Any hint really appreciated.

Could anyone with experience direct me please.

Last edited by ComputGuy; 09-23-2013 at 12:23 PM.
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david tool, enrichment, gene expression

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