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Old 09-23-2013, 09:03 AM   #1
ComputGuy
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Location: Michigan

Join Date: Sep 2013
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Question Enrichment analysis with DAVID tool - question

Hi All,

I am still new in the field and I have a question please.

I have a dataset of gene expressions and I am running biclustering methods over them. The dataset is colon cancer dataset, When I get the new biclusters I want to do biological validation; enrichment analysis to find how many genes are enriched in each bicluster. I want to use DAVID tool for that.
My question is when I upload my gene set to DAVID tool, I choose "Functional Annotation Clustering" then I have set of clusters for the set of genes that I uploaded with different gene enrichment score. How can I find "Proportion of biclusters significantly enriched" as it has been done in Figure 3 of this paper "A systematic comparison and evaluation of biclustering methods
for gene expression data"
http://bioinformatics.oxfordjournals....full.pdf+html

Any help please? Any hint really appreciated.

Could anyone with experience direct me please.
Thanks!

Last edited by ComputGuy; 09-23-2013 at 12:23 PM.
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