Which software for analysing mutational signatures in cancer genomes is best?

PeterOD · 01-05-2018, 07:49 AM

I am currently researching mutational signatures in Cancer genomes (see here for an explanation: http://cancer.sanger.ac.uk/cosmic/signatures). I am using the DeconstructSigs package in R to analyze the data I have available. I was just wondering, do there exist other software for performing the same task that are seen as better? I know of the existence of the SomaticSignatures package but am unclear whether it is any better or worse than DeconstructSigs.

Any advice would be greatly appreciated!

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01-05-2018, 07:49 AM	#1
PeterOD Junior Member Location: Dublin, Ireland Join Date: Oct 2017 Posts: 1	Which software for analysing mutational signatures in cancer genomes is best? I am currently researching mutational signatures in Cancer genomes (see here for an explanation: http://cancer.sanger.ac.uk/cosmic/signatures). I am using the DeconstructSigs package in R to analyze the data I have available. I was just wondering, do there exist other software for performing the same task that are seen as better? I know of the existence of the SomaticSignatures package but am unclear whether it is any better or worse than DeconstructSigs. Any advice would be greatly appreciated!