Hi there
I am comparing exome seq data from 3 platforms; Solid4, Solid5500 and HiSeq(Illumina).
I have set the min. depth to 10 but I am wondering if this present the same meaning across all platforms.
Because of different read lenghts etc, could it be that depth 10 in platform A gives the same reliability in variant calling as depth 8 in platform B?
Which factors would you consider when comparing the meaning of depth between platforms?
Thanks,
Louise
I am comparing exome seq data from 3 platforms; Solid4, Solid5500 and HiSeq(Illumina).
I have set the min. depth to 10 but I am wondering if this present the same meaning across all platforms.
Because of different read lenghts etc, could it be that depth 10 in platform A gives the same reliability in variant calling as depth 8 in platform B?
Which factors would you consider when comparing the meaning of depth between platforms?
Thanks,
Louise
Comment