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  • Live Webinar on UMI-powered Ultra-sensitive Variant Calling on 13 Dec 2017

    Live Webinar on Unique Molecular Identifier-powered Ultra-sensitive Variant Calling using Strand NGS - Case Study by Dr.Pandurang Kolekar, on 13 Dec at 2:30 PM IST and 9:30 PM IST

    Abstract:
    Unique Molecular Identifiers (UMIs) are short random nucleotide sequences that are increasingly being used in high-throughput sequencing experiments. In this webinar, we will highlight the UMI-friendly features of Strand NGS v3.1 including support for handling well known and customised UMI libraries, QC metrics, consensus alignment, UMI-based family size filters for read list, genome browser enabled with UMI-specific features and filters, UMI-aware variant calling parameters, and exporting UMI-tagged aligned samples. These all features together empower users to harness the potential of UMI-tagged NGS data for deeper insights. A case study demonstrating application of these UMI-based features in Strand NGS for low frequency variant calling in cfDNA sample will be presented.

    UMI-tagged NGS libraries allow, ultra-sensitive detection of low frequency variants from liquid biopsy samples using DNA-Seq and accurate quantification of transcript-level expression using RNA-Seq. The recent release of Strand NGS v3.1, is equipped with the necessary features to efficiently analyse UMI-tagged NGS data helping researchers and labs involved in rare variant calling like in cfDNA based cancer diagnostics, and accurate transcript quantification with RNA-Seq.

    To attend register here: http://www.strand-ngs.com/webinar_registration

  • #2
    Read through this article on 'UMI-Powered Ultra-Sensitive Variant Calling with Strand NGS' to know more about the unique molecular identifiers, challenges and oppurtunities
    Background Unique Molecular Identifiers (UMIs) are short random nucleotide sequences (4 - 20 bases), which are increasingly being used in high-throughput next generation sequencing (NGS) experiments to distinguish individual DNA/cDNA molecules [1, 2]. Following terms are synonymous with UMIs: Unique

    Do register for the upcoming webinar by Dr.Pandurang Kolekar scheduled on 13 Dec at 2:30 PM IST and 9:30 PM IST. Register for webinar at http://www.strand-ngs.com/webinar_registration

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    • #3
      Webinar: UMI-powered ultra sensitive variant calling in Strand NGS

      Hurry! Limited seats available. To attend, register at
      This webinar showcases an NGS data analysis study of two geographically dispersed SARS-CoV2 datasets.

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