I thought I recently read a paper detailing poorer read mapping to a reference genome if the read contained the non-reference allele. This wouldn't be a total surprise, but I think the article detailed it. But now I can't find the paper again.
Did anyone else see this? Has anyone here tried to quantitate this phenomenon.
thanks in advance.
Did anyone else see this? Has anyone here tried to quantitate this phenomenon.
thanks in advance.
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