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Old 07-17-2011, 10:11 PM   #1
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Location: CN

Join Date: May 2011
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Smile Combined assembly of 454 and Solexa reads

I have got both 454 long reads(SR & PE, 400bp) and Solexa reads(100-150bp) for a genome, however, the combined assembly result is not as good as expected, using velvet, newbler, etc. Anyone who has such experiences please give some suggestions on the tool selection, thanks!
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Old 07-18-2011, 06:50 AM   #2
Location: Flagstaff, AZ

Join Date: Feb 2010
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I'd try Mira:

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