Unconfigured Ad

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts
  • jmaury
    Junior Member
    • Mar 2008
    • 4

    New software: G-Morse : Annotating genomes with massive-scale RNA-sequencing

    Hi all,

    I would like to introduce G-Mo.R-Se (Gene Modelling using RNA-Seq), an approach aimed at building gene models directly from RNA-Seq.
    More detailed information here.

    -------------------------------------------------------------------------------------------------------------
    Genome Biol. 2008 Dec 16;9(12):R175.
    Annotating genomes with massive-scale RNA-sequencing.
    Denoeud F, Aury JM, Da Silva C, Noel B, Rogier O, Delledone M, Morgante M, Valle G, Wincker P, Scarpelli C, Jaillon O, Artiguenave F.

    ABSTRACT: Next generation technologies enable massive-scale cDNA sequencing (so-called RNA-Seq). Mainly because of the difficulty to align short reads on exon/exon junctions, no attempts have been made so far to use RNA-Seq for building gene models de novo, i.e. in the absence of a set of known genes and/or splicing events. We present G-Mo.R-Se (Gene Modelling using RNA-Seq), an approach aimed at building gene models directly from RNA-Seq and demonstrate its utility on the grapevine genome.

    PMID: 19087247 [PubMed - as supplied by publisher]
  • odelfour
    Junior Member
    • Oct 2008
    • 8

    #2
    Nice work!

    olivier

    Comment

    • xwu
      Member
      • Dec 2007
      • 10

      #3
      Is there a downloadable tool available for this?

      Comment

      • Chipper
        Senior Member
        • Mar 2008
        • 323

        #4
        G-Mo.R-Se: Gene MOdeling using RNA-Seq program, CEA, DSV, Institut de Génomique, Genoscope

        Comment

        • xwu
          Member
          • Dec 2007
          • 10

          #5
          Thanks a lot. Chipper. Have you tested it? I will definitely give it a try.

          Comment

          Latest Articles

          Collapse

          • SEQadmin2
            From Collection to Sequencing: Why Sample Preparation and Preservation Define Sequencing Data
            by SEQadmin2


            Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.


            The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
            ...
            06-02-2026, 10:05 AM
          • SEQadmin2
            Single-Cell Sequencing at an Inflection Point: Early Impacts of New Platforms and Emerging Trends
            by SEQadmin2


            With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.


            Introduction

            Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...
            05-22-2026, 06:42 AM
          • SEQadmin2
            Environmental Genomics in the Age of NGS: From Microbes to Conservation Strategies
            by SEQadmin2

            Studying ecosystems means dealing with complex, multi-species communities that are hard to observe at scale. This complexity, however, hides many important questions to be answered, from how biogeochemical cycles work and how climate change can affect species distribution to how conservation strategies can work best.


            Genomics, particularly since the expansion of NGS, has transformed ecosystem ecology. By sequencing environmental DNA, we can now assess biodiversity without direct...
            05-06-2026, 09:04 AM

          ad_right_rmr

          Collapse

          News

          Collapse

          Topics Statistics Last Post
          Started by SEQadmin2, Today, 08:59 AM
          0 responses
          7 views
          0 reactions
          Last Post SEQadmin2  
          Started by SEQadmin2, 06-02-2026, 12:03 PM
          0 responses
          21 views
          0 reactions
          Last Post SEQadmin2  
          Started by SEQadmin2, 06-02-2026, 11:40 AM
          0 responses
          14 views
          0 reactions
          Last Post SEQadmin2  
          Started by SEQadmin2, 05-28-2026, 11:40 AM
          0 responses
          29 views
          0 reactions
          Last Post SEQadmin2  
          Working...