Spaces are still available on this course, in which we will devote a whole day to the ENA's Sequence Read Archive (http://www.ebi.ac.uk/ena/), covering automated submissions, our new spreadsheet-based submission tool and new ways in which data can be retrieved.
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM