Molecular Biologist/Bioinformatics Postdoc

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Seeking qualified candidate to join my research group, focused on the molecular mechanisms underlying neural differentiation, particularly from human embryonic stem cells. Our recent work uncovered patterns of microRNA and mRNA changes during differentiation in rat neural precursors, human ES cells, and human MSC. Proposed projects include the use of a new Applied Biosystems SOLiD sequencing system to identify novel microRNAs expressed during neural specification in human ES cells. We use bioinformatics to extract both general patterns and specific examples for hypothesis-driven laboratory experiments using standard techniques of molecular biology. Our goal is to learn how to program stem cells to develop therapeutic transplants for spinal cord injury and related conditions.

A recent Ph.D. in molecular biology and/or bioinformatics is required. Experience with basic molecular biology methods (e.g., PCR, microarrays, promoter studies, regulated expression systems) stem cell culture techniques is preferred. Knowledge of bioinformatics methods related to gene expression studies (such as R/BioConductor) is preferred, as is programming experience with MySQL, PHP and/or PERL/BioPERL. At this time we can only consider U.S. citizens or holders of a valid green card. The position is available immediately.

To apply, please visit our group's web site: http://www.ngelab.org and click the "Positions" heading.