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  • fadista
    Member
    • Sep 2008
    • 37
    #1

    exome sequencing - big coverage differences

    Hi,

    I would like to know if any of you had experience with Tru-Seq exome sequencing and if you see that there is a lot of variation in genome coverage between the samples, even within the same multiplex group.

    Many thanks
    Tags: coverage, exome analysis
    • NextGenSeq
      Senior Member
      • Apr 2009
      • 482
      #2
      We've seen big differences between barcoded samples not so much with non-barcoded samples.

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