cuffdiff log2 value

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guzhi100

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Join Date: Feb 2012

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#1

cuffdiff log2 value

04-26-2012, 06:52 AM

Hi,

I am analyzing my RNA-Seq data. After running cuffdiff, I got a list of differentially expressed transcrpts or genes.

As far as I know, log2 value = fold change. However, there are minus values. Is this possible?? log2 value can not be minus. Did I miss something??

Looking forward to your help.

Thanks in advance.

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kopi-o

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#2

04-26-2012, 08:20 AM

The log2 value can most definitely be negative. Why not?
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sdriscoll

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#3

04-26-2012, 09:00 PM

Try log2(0.5) and log2(2). Log2 scale is convenient.

/* Shawn Driscoll, Gene Expression Laboratory, Pfaff
Salk Institute for Biological Studies, La Jolla, CA, USA */
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