Hello all,
I was wondering if anyone knows how to identify and remove only optical duplicates from RNAseq SE data. I have looked into Picard but it was only able to calculate the number of optical duplicates and no option was provided to remove only the optical duplicates. I do not want to remove PCR duplicates especially from single end reads to avoid losing lots of information
Hoping for a good response!
I was wondering if anyone knows how to identify and remove only optical duplicates from RNAseq SE data. I have looked into Picard but it was only able to calculate the number of optical duplicates and no option was provided to remove only the optical duplicates. I do not want to remove PCR duplicates especially from single end reads to avoid losing lots of information
Hoping for a good response!
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