Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • apredeus
    Senior Member
    • Jul 2012
    • 151

    #1

    Does any large resequencing project have a genuinely hg38 VCF?

    In one of our projects we are comparing hg19-related assemblies (such as b37 etc) to hg38, and basically discovered that there are no available VCF files for the newest reference. I understand that it requires a tremendous effort and that's why most of the large consortia are reluctant to switch. However it seems like it would have to happen sooner or later. So, maybe some of the newest projects did in fact process everything in hg38?

    Please let me know if you know of any such cases. Thank you in advance.
  • lindenb
    Senior Member
    • Apr 2010
    • 143

    #2
    cross posted https://www.biostars.org/p/186797/

    Comment

    • apredeus
      Senior Member
      • Jul 2012
      • 151

      #3
      Up. Any ideas? I find it hard to believe that no modern consortium haven't even tried that.

      Comment

      Latest Articles

      Collapse

      • SEQadmin2
        Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
        by SEQadmin2



        CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

        Despite this, “CRISPR helped turn genome editing from a specialized technique into
        ...
        07-31-2026, 11:01 AM
      • SEQadmin2
        Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
        by SEQadmin2


        Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

        The systematic characterization of the human proteome has
        ...
        07-20-2026, 11:48 AM

      ad_right_rmr

      Collapse

      News

      Collapse

      Topics Statistics Last Post
      Started by SEQadmin2, 08-06-2026, 07:41 AM
      0 responses
      22 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 08-03-2026, 10:13 AM
      0 responses
      33 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 07-31-2026, 02:55 AM
      0 responses
      43 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 07-24-2026, 12:17 PM
      0 responses
      26 views
      0 reactions
      Last Post SEQadmin2  
      Working...