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DNA Electronics partners with Roche to develop semiconductor based sequencing system
DNA Electronics, a fabless semiconductor provider of solutions for real-time DNA and RNA analysis, announced today that it has entered a partnership with 454 Life Sciences, a Roche Company. The collaboration will focus on the development of a low-cost, high-throughput, long read, high density DNA sequencing system. As part of the agreement, DNA Electronics has signed a non-exclusive licence to provide relevant IP from its proprietary semiconductor technology portfolio to Roche. This technology which enables sensitive detection of nucleotide incorporation during sequencing will build on 454 Life Sciences’ current pyrosequencing-based platform. The collaboration leverages DNA Electronics’ unique knowledge of semiconductor design and expertise in pH-mediated detection of nucleotide insertions with 454 Life Sciences’ long read sequencing chemistry to produce a seamless evolution from optical detection to low-cost, highly scalable electrochemical detection.
pdf of press release: http://www.dnae.co.uk/images/2010-11...%20License.pdf -
And it will be called "Ion Current"?...Comment
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This was pretty interesting to me also...especially since DNA Electronics licensed their tech to Ion Torrent as well.
Maybe we're heading for a big IP battle! Exciting...Comment
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Exciting indeed eco
I think the next 2 years is going to be great viewing for the impartial observer - and this site will probably give a pretty good front row seat!Comment
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Sample prep for ISFETs
I wonder if emPCR IP for sample prep will also fall into the fray. All the ISFET sensor tech will need a bead in a well for measurement until solid state nanopores come along.Comment
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I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...06-18-2026, 07:11 AM -
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM
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