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Introductions
New here? Stop in and introduce yourself. Where you are, what you work on, etc.
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Last Post: Intro
2,280 4,404
abolerbarros
Sequencing Resources
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358 826
News
News about the latest advances and discoveries in sequencing and related technologies.
Topics: 300 Posts: 303
300 303
Core Facilities
Dealing with customer samples, data, and the challenges that come with both?
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127 577
General
Any topic/question that does not fit into the subcategories below. If you're unsure of where to put something, ask in here!
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2,618 7,821
Webinar Series
Upcoming and on-demand webinars by SEQanswers and its partners.
Topics: 40 Posts: 56
Last Post: On-Demand Webinars
40 56
seqadmin
Literature Watch
Discussion of any scientific study related to high content or next generation genomics. Whole genome association, metagenomics, digital gene expression, etc.
Topics: 41,653 Posts: 42,332
41,653 42,332
Sequencing Technologies/Companies
Complete Genomics
DNA single-strand circularization followed by rolling circle amplification (RCA) to form DNA nanoballs for DNBSEQ.
Topics: 53 Posts: 165
53 165
Element Biosciences
Avidity sequencing - multivalent nucleotide ligands on dye-labeled cores to form polymerase-polymer nucleotide complexes bound to clonal copies of DNA targets.
Topics: 2 Posts: 5
2 5
Illumina (Solexa)
Bridged amplification & clustering followed by sequencing by synthesis.
Topics: 3,059 Posts: 16,726
3,059 16,726
Ion Torrent
Integrated electronic detection of protons released upon base incorporation. (Thermo Fisher Scientific)
Topics: 392 Posts: 2,175
392 2,175
jyheo
by jyheo
Oxford Nanopore
Single-molecule sequencing via a protein nanopore.
Topics: 118 Posts: 599
118 599
Pacific Biosciences
Single-molecule real-time observation of DNA polymerase using zero-mode waveguide (ZMW) optical confinement nanostructures or sequencing by binding (SBB)
Topics: 385 Posts: 2,176
385 2,176
Singular Genomics
Optical ensemble sequencing by synthesis via fluorescently labeled reversible terminated nucleotides.
Topics: 0 Posts: 0
0 0
Ultima Genomics
Open flow cell design on a circular wafer and mostly natural nucleotides that allow optical end-point detection without reversible terminators.
Topics: 0 Posts: 0
0 0
Sanger/Dye Terminator
Automated dye terminator ("Sanger") chemistries
Topics: 76 Posts: 278
76 278
Service Providers
Discussions about next gen sequencing service providers, reviews & experiences, etc. No overtly commercial content permitted without prior approval.
Topics: 79 Posts: 480
79 480
Archived Forums
A place for discussion of older forums and sequencing technologies.
Topics: 1,361 Posts: 7,278
Last Post: Rapid Libraries
1,361 7,278
pmiguel
by pmiguel
Sub-Forums:
UK - Cambridge (37/67)
The Pipeline (81/587)
SOLiD (462/2,440)
454 Pyrosequencing (743/3,966)
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Bioinformatics
Bioinformatics
Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
Topics: 22,114 Posts: 103,084
22,114 103,084
Events / Conferences
Relevant events or scientific conferences that may be of interest to the community. (Mgmt reserves right to limit commercial content without approval.)
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784 1,299
Jobs Forums
Industry Jobs!
Job listings at companies that sponsor SEQanswers.com! Interested in posting a job? Contact admin@ for access.
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222 253
vivianshaw
Academic/Non-Profit Jobs
Post and look for academic, non-profit, or other non-industrial jobs here.
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1,606 1,822
Applications Forums
Sample Prep / Library Generation
Techniques and protocol discussions on sample preparation, library generation, methods and ideas
Topics: 2,204 Posts: 9,904
2,204 9,904
Single Cell Sequencing
Techniques, discussions, and applications of single cell sequencing.
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8 15
Genomic Resequencing
Variant discovery in previously sequenced genomes/regions
Topics: 278 Posts: 991
278 991
De novo discovery
Wandering without a reference? Post here
Topics: 342 Posts: 1,701
342 1,701
Metagenomics
Ever wonder what's growing in that hot spring or glacier?
Topics: 273 Posts: 852
273 852
Epigenetics
Any non-primary sequence heritable modification of genetic material. ChIP-SEQ, DNA methylation (Bisulfite-SEQ), chromatin modifications (methylation, acetylation, etc), non coding RNA.
Topics: 357 Posts: 1,578
357 1,578
RNA Sequencing
Application of sequencing to RNA analysis (RNA-Seq, whole transcriptome, SAGE, expression analysis, novel organism mining, splice variants)
Topics: 2,872 Posts: 11,431
2,872 11,431
Clinical Sequencing
Discuss issues unique to clinical sequencing.
Topics: 42 Posts: 107
42 107
Personalized Genomics
Personalized Genomics
Efforts to understand one's own genome. Companies such as 23andme, Navigenics, Knome, DNADirect, and private efforts like the Personal Genome Project. Ethics, privacy, security, all of it goes here.
Topics: 58 Posts: 291
58 291
Site News
Site Announcements
Announcements regarding SEQanswers
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seqadmin
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48 657

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Recent Articles

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  • seqadmin
    Recent Innovations in Spatial Biology


    Spatial biology is an exciting field that encompasses a wide range of techniques and technologies aimed at mapping the organization and interactions of various biomolecules in their native environments. As this area of research progresses, new tools and methodologies are being introduced, accompanied by efforts to establish benchmarking standards and drive technological innovation.

    3D Genomics
    While spatial biology often involves studying proteins and RNAs in their...
    01-01-2025, 07:30 PM
  • seqadmin
    Advancing Precision Medicine for Rare Diseases in Children




    Many organizations study rare diseases, but few have a mission as impactful as Rady Children’s Institute for Genomic Medicine (RCIGM). “We are all about changing outcomes for children,” explained Dr. Stephen Kingsmore, President and CEO of the group. The institute’s initial goal was to provide rapid diagnoses for critically ill children and shorten their diagnostic odyssey, a term used to describe the long and arduous process it takes patients to obtain an accurate...
    12-16-2024, 07:57 AM
  • seqadmin
    Recent Advances in Sequencing Technologies



    Innovations in next-generation sequencing technologies and techniques are driving more precise and comprehensive exploration of complex biological systems. Current advancements include improved accessibility for long-read sequencing and significant progress in single-cell and 3D genomics. This article explores some of the most impactful developments in the field over the past year.

    Long-Read Sequencing
    Long-read sequencing has seen remarkable advancements,...
    12-02-2024, 01:49 PM

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