Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • stringtie error: GFF not recognized

    Hello,
    I'm trying to run stringtie with a reference genome, and I'm getting the following error:

    WARNING: no reference transcripts were found for the genomic sequences where reads were mapped!
    Please make sure the -G annotation file uses the same naming convention for the genome sequences.

    Similar posts indicate that there is some inconsistency between the reference genome fasta file that was used in the hisat2 step and the gff3 or gtf file that is used for stringtie. I can't see any inconsistency in my case. I'm stumped. I really, really hope someone can help!

    The reference genome fasta headers look like this:
    Code:
    >scaffold_1_length_46699537
    >scaffold_2_length_45526029
    >scaffold_3_length_45460755
    >scaffold_4_length_44284954
    >scaffold_5_length_43231337

    The first few lines of the gff look like this:
    Code:
    ##gff-version 3
    scaffold1_length_46699537       .       contig  1       46699537        .       .       .       ID=scaffold1_length_46699537;Name=scaffold1_length_46699537
    scaffold1_length_46699537       maker   gene    1701    4304    .       -       .       ID=Mlong585_00001;Name=Mlong585_00001;Alias=augustus-scaffold1_length_46699537-processed-gene-0.17;
    scaffold1_length_46699537       maker   mRNA    1701    4304    .       -       .       ID=Mlong585_00001-RA;Parent=Mlong585_00001;Name=Mlong585_00001-RA;Alias=augustus-scaffold1_length_46699537-processed-gene-0.17-mRNA-1;_AED=1.00
    scaffold1_length_46699537       maker   exon    1701    3837    .       -       .       ID=Mlong585_00001-RA:exon:78;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   CDS     1701    3837    .       -       1       ID=Mlong585_00001-RA:cds;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   exon    4012    4097    .       -       .       ID=Mlong585_00001-RA:exon:79;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   CDS     4012    4097    .       -       0       ID=Mlong585_00001-RA:cds;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   CDS     4173    4304    .       -       0       ID=Mlong585_00001-RA:cds;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   exon    4173    4304    .       -       .       ID=Mlong585_00001-RA:exon:80;Parent=Mlong585_00001-RA;
    scaffold1_length_46699537       maker   gene    4819    8990    .       +       .       ID=Mlong585_00002;Name=Mlong585_00002;Alias=snap-scaffold1_length_46699537-processed-gene-0.25;
    scaffold1_length_46699537       maker   mRNA    4819    8990    .       +       .       ID=Mlong585_00002-RA;Parent=Mlong585_00002;Name=Mlong585_00002-RA;Alias=snap-scaffold1_length_46699537-processed-gene-0.25-mRNA-1;_AED=1.00;_QI
    scaffold1_length_46699537       maker   exon    4819    6558    .       +       .       ID=Mlong585_00002-RA:exon:48;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     4819    6558    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     7278    7432    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    7278    7432    .       +       .       ID=Mlong585_00002-RA:exon:49;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     7462    7531    .       +       1       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    7462    7531    .       +       .       ID=Mlong585_00002-RA:exon:50;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     7567    7629    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    7567    7629    .       +       .       ID=Mlong585_00002-RA:exon:51;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     7639    7974    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    7639    7974    .       +       .       ID=Mlong585_00002-RA:exon:52;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     8000    8056    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    8000    8056    .       +       .       ID=Mlong585_00002-RA:exon:53;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     8800    8856    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    8800    8856    .       +       .       ID=Mlong585_00002-RA:exon:54;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   CDS     8958    8990    .       +       0       ID=Mlong585_00002-RA:cds;Parent=Mlong585_00002-RA;
    scaffold1_length_46699537       maker   exon    8958    8990    .       +       .       ID=Mlong585_00002-RA:exon:55;Parent=Mlong585_00002-RA

Latest Articles

Collapse

  • seqadmin
    Advancing Precision Medicine for Rare Diseases in Children
    by seqadmin




    Many organizations study rare diseases, but few have a mission as impactful as Rady Children’s Institute for Genomic Medicine (RCIGM). “We are all about changing outcomes for children,” explained Dr. Stephen Kingsmore, President and CEO of the group. The institute’s initial goal was to provide rapid diagnoses for critically ill children and shorten their diagnostic odyssey, a term used to describe the long and arduous process it takes patients to obtain an accurate...
    12-16-2024, 07:57 AM
  • seqadmin
    Recent Advances in Sequencing Technologies
    by seqadmin



    Innovations in next-generation sequencing technologies and techniques are driving more precise and comprehensive exploration of complex biological systems. Current advancements include improved accessibility for long-read sequencing and significant progress in single-cell and 3D genomics. This article explores some of the most impactful developments in the field over the past year.

    Long-Read Sequencing
    Long-read sequencing has seen remarkable advancements,...
    12-02-2024, 01:49 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 12-17-2024, 10:28 AM
0 responses
33 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-13-2024, 08:24 AM
0 responses
49 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-12-2024, 07:41 AM
0 responses
34 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-11-2024, 07:45 AM
0 responses
46 views
0 likes
Last Post seqadmin  
Working...
X