Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • dindel, exomes and chromosome 10

    Hi all,

    I run dindel as part of workflow which I do for dna seq, which large percent is exome samples. I've noticed something quite odd with regards to dindel stage 3.

    I run stage 3 parallel using cluster. I split the input with '--numWindowsPerFile 1500' currently. Most of the executions take between 20 and 50 minutes to run. Some take more. However I've noticed that in many cases there is one that takes a lot more time (can take several days). That seems to happen in situations where the chromosomal position is in chr 10 and 42Mb. Has anyone else noticed anything similar? There seems to be high number of haplotypes printed in log*, but I did check this for each file in one sample and mean haplotype of all lines per file doesn't seem to follow execution time that file.

    * eg the it has something like this:
    [empiricalDistributionMethod] Number of haplotypes: 136

Latest Articles

Collapse

  • seqadmin
    Advancing Precision Medicine for Rare Diseases in Children
    by seqadmin




    Many organizations study rare diseases, but few have a mission as impactful as Rady Children’s Institute for Genomic Medicine (RCIGM). “We are all about changing outcomes for children,” explained Dr. Stephen Kingsmore, President and CEO of the group. The institute’s initial goal was to provide rapid diagnoses for critically ill children and shorten their diagnostic odyssey, a term used to describe the long and arduous process it takes patients to obtain an accurate...
    12-16-2024, 07:57 AM
  • seqadmin
    Recent Advances in Sequencing Technologies
    by seqadmin



    Innovations in next-generation sequencing technologies and techniques are driving more precise and comprehensive exploration of complex biological systems. Current advancements include improved accessibility for long-read sequencing and significant progress in single-cell and 3D genomics. This article explores some of the most impactful developments in the field over the past year.

    Long-Read Sequencing
    Long-read sequencing has seen remarkable advancements,...
    12-02-2024, 01:49 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 12-17-2024, 10:28 AM
0 responses
33 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-13-2024, 08:24 AM
0 responses
48 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-12-2024, 07:41 AM
0 responses
34 views
0 likes
Last Post seqadmin  
Started by seqadmin, 12-11-2024, 07:45 AM
0 responses
46 views
0 likes
Last Post seqadmin  
Working...
X