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hanshart

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Join Date: Nov 2011

Posts: 27
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Bowtie depth-first vs. best-first

03-14-2012, 11:11 AM

Hi

Can anyone explain the difference between the depth-first backtracking approach and the --best (best-first) approach in Bowtie? Or in other words, what is depth-first doing and why does it not report the very best alignment?
Thank you
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