UCSC genome browser uses binning strategy to retrieve genes more efficiently than simply creating a B-tree on the start and end coordinates. This certainly serves the purpose well because query ranges is not a strengthen of B-tree. But binning + B-tree basically provides a crude approximation to R-tree (using spatial index) that has already been implemented in MySQL. I'm wondering why is this spatial index not used in the first place? Is it because the spatial index is a relatively new feature that was not implemented in MySQL when the UCSC GB was developed? Just curious.
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by seqadmin
Many organizations study rare diseases, but few have a mission as impactful as Rady Children’s Institute for Genomic Medicine (RCIGM). “We are all about changing outcomes for children,” explained Dr. Stephen Kingsmore, President and CEO of the group. The institute’s initial goal was to provide rapid diagnoses for critically ill children and shorten their diagnostic odyssey, a term used to describe the long and arduous process it takes patients to obtain an accurate...-
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12-16-2024, 07:57 AM -
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by seqadmin
Innovations in next-generation sequencing technologies and techniques are driving more precise and comprehensive exploration of complex biological systems. Current advancements include improved accessibility for long-read sequencing and significant progress in single-cell and 3D genomics. This article explores some of the most impactful developments in the field over the past year.
Long-Read Sequencing
Long-read sequencing has seen remarkable advancements,...-
Channel: Articles
12-02-2024, 01:49 PM -
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