Hi all,
We have performed CNV study specific to a phenotype in humans and performed some bioinformatic analysis to prioritize the genes and picked up a gene based on the biological processes and functions in which the gene is involved.
And now we need to prove that this gene is the causative gene for the phenotype (complex phenotype). Could someone suggest some molecular biology techniques i.e. functional studies which could be performed in this case?
Any suggestions are highly valuable.
We have performed CNV study specific to a phenotype in humans and performed some bioinformatic analysis to prioritize the genes and picked up a gene based on the biological processes and functions in which the gene is involved.
And now we need to prove that this gene is the causative gene for the phenotype (complex phenotype). Could someone suggest some molecular biology techniques i.e. functional studies which could be performed in this case?
Any suggestions are highly valuable.
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