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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,620 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,215 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Mindbomb, 06-13-2012, 07:46 AM
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1 response
3,866 views
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by zoolium
04-22-2013, 08:04 AM
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Started by Dolphin22, 04-22-2013, 07:11 AM
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0 responses
1,062 views
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by Dolphin22
04-22-2013, 07:11 AM
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Started by yaximik, 04-18-2013, 04:45 PM
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9 responses
9,023 views
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by syfo
04-22-2013, 05:22 AM
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Started by Palgrave, 04-16-2012, 06:34 AM
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8 responses
5,612 views
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by syfo
04-22-2013, 05:11 AM
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Started by himanshu04, 04-10-2013, 10:53 AM
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2 responses
1,594 views
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by milesgr
04-22-2013, 05:02 AM
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Started by Charitra, 04-21-2013, 05:24 PM
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2 responses
1,505 views
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by Charitra
04-22-2013, 05:00 AM
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Started by carolW, 04-18-2013, 02:47 AM
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3 responses
6,065 views
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by GenoMax
04-22-2013, 03:35 AM
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Started by scondo, 04-22-2013, 01:08 AM
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0 responses
1,013 views
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by scondo
04-22-2013, 01:08 AM
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Started by dphansti, 04-18-2013, 05:09 PM
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2 responses
1,395 views
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by maasha
04-22-2013, 12:17 AM
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Started by swNGS, 04-19-2013, 04:49 AM
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4 responses
2,915 views
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Last Post
by Zaag
04-21-2013, 11:52 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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8 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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