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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,369 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,283 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by tellsparck, 01-10-2013, 11:29 AM
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10 responses
2,873 views
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by billstevens
02-02-2013, 10:49 AM
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Started by SHeaph, 02-02-2013, 07:42 AM
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0 responses
1,318 views
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by SHeaph
02-02-2013, 07:42 AM
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Started by efoss, 01-31-2013, 05:04 PM
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3 responses
2,908 views
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by efoss
02-01-2013, 04:09 PM
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Started by winsettz, 01-31-2013, 07:42 AM
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2 responses
1,850 views
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by winsettz
02-01-2013, 12:58 PM
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Started by ihelbig, 01-04-2013, 05:50 AM
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5 responses
6,369 views
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by ECO
02-01-2013, 12:48 PM
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Started by Jerry_Zhao, 01-30-2013, 08:59 AM
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8 responses
4,841 views
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by Jerry_Zhao
02-01-2013, 12:01 PM
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Started by camelbbs, 01-09-2013, 11:34 AM
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3 responses
1,727 views
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by camelbbs
02-01-2013, 11:06 AM
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Started by yzzhang, 01-31-2013, 08:49 AM
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2 responses
3,935 views
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by yzzhang
02-01-2013, 08:50 AM
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Started by kalinka23, 02-01-2013, 08:34 AM
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0 responses
11 views
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by kalinka23
02-01-2013, 08:34 AM
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Started by Jetse, 02-01-2013, 07:53 AM
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0 responses
1,448 views
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Last Post
by Jetse
02-01-2013, 07:53 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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7 views
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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