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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,730 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,708 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by milo0615, 09-01-2016, 04:53 PM
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1 response
2,456 views
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Started by Rocketsloth, 06-19-2018, 12:34 AM
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0 responses
1,014 views
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by Rocketsloth
06-19-2018, 12:34 AM
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Started by swebb, 01-07-2014, 07:54 AM
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15 responses
16,318 views
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by finixtree
06-14-2018, 05:39 AM
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Started by szy0931, 06-13-2018, 02:04 PM
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3 responses
1,415 views
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by Bukowski
06-14-2018, 05:28 AM
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Started by skannan4, 06-13-2018, 09:01 AM
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0 responses
2,021 views
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by skannan4
06-13-2018, 09:01 AM
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Started by eadonyo, 06-08-2018, 01:48 AM
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7 responses
1,608 views
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by finswimmer
06-13-2018, 04:40 AM
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Started by lfaller, 05-24-2018, 12:08 PM
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1 response
4,016 views
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by neavemj
06-11-2018, 03:59 PM
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Started by fznajar, 06-07-2018, 12:43 PM
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9 responses
5,743 views
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by fznajar
06-11-2018, 02:47 PM
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Started by rammohanshukla, 06-11-2018, 12:38 PM
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0 responses
1,075 views
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Started by standonn, 01-12-2015, 03:16 AM
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1 response
3,587 views
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by al-ash
06-10-2018, 07:13 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-24-2026, 10:32 AM
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14 views
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by SEQadmin2
08-24-2026, 10:32 AM
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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33 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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37 views
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by SEQadmin2
08-18-2026, 10:05 AM
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