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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,619 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,180 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by manianslab, 06-21-2012, 01:37 PM
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2 responses
4,192 views
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by manianslab
07-13-2012, 12:56 PM
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Started by genelab, 07-12-2012, 07:11 PM
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4 responses
2,536 views
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by shyam_la
07-13-2012, 10:31 AM
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Started by colinmolter, 07-13-2012, 09:59 AM
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0 responses
2,152 views
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by colinmolter
07-13-2012, 09:59 AM
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Started by krawitz, 07-13-2012, 07:36 AM
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2 responses
2,390 views
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by swbarnes2
07-13-2012, 09:37 AM
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Started by yifangt, 07-12-2012, 12:40 PM
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4 responses
3,715 views
0 reactions
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by scalabrin
07-13-2012, 08:52 AM
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Started by Lisa Jane Cross, 07-10-2012, 05:04 AM
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3 responses
2,184 views
0 reactions
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by RDW
07-13-2012, 06:53 AM
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Started by ranjani, 07-12-2012, 09:18 PM
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1 response
1,517 views
0 reactions
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by krobison
07-13-2012, 06:01 AM
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Started by Seq84, 02-15-2011, 12:56 AM
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3 responses
4,231 views
0 reactions
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by swjh
07-13-2012, 04:05 AM
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Started by yujiro, 07-13-2012, 01:09 AM
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0 responses
2,471 views
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by yujiro
07-13-2012, 01:09 AM
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Started by ourgenome, 07-13-2012, 01:01 AM
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0 responses
2,128 views
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by ourgenome
07-13-2012, 01:01 AM
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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6 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
11 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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