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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,678 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,751 views
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by ECO
12-25-2009, 06:45 PM
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Started by erika_, 03-07-2024, 03:04 AM
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136 views
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by erika_
03-07-2024, 03:04 AM
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Started by arredondoea, 03-06-2024, 12:32 PM
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339 views
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by arredondoea
03-06-2024, 12:32 PM
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Started by ecSeq Bioinformatics, 03-05-2024, 01:22 AM
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140 views
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Started by roussine, 03-04-2024, 06:33 PM
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99 views
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by roussine
03-04-2024, 06:33 PM
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Started by bioinformatics.ca, 02-29-2024, 11:28 AM
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278 views
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Started by prairie-guy, 02-25-2024, 02:42 PM
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151 views
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by prairie-guy
02-25-2024, 02:42 PM
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Started by Brian Bushnell, 06-04-2014, 03:03 PM
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129 responses
99,013 views
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by mcoyne
02-21-2024, 08:40 AM
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Started by ghimbikal, 02-20-2024, 07:55 AM
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133 views
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by ghimbikal
02-20-2024, 07:55 AM
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Started by ayan.chanda, 02-15-2024, 08:49 AM
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247 views
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by ayan.chanda
02-15-2024, 08:49 AM
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Started by kjaja, 01-31-2024, 02:57 AM
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1 response
287 views
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by fchatonnet
02-14-2024, 01:09 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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18 views
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by SEQadmin2
08-06-2026, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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33 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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43 views
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by SEQadmin2
07-31-2026, 02:55 AM
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