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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,627 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,238 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by allo, 03-26-2012, 07:26 PM
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0 responses
2,131 views
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by allo
03-26-2012, 07:26 PM
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Blat search
by honey
Started by honey, 03-26-2012, 08:42 AM
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4 responses
3,485 views
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by honey
03-26-2012, 12:14 PM
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Started by RTK45, 03-26-2012, 12:13 PM
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0 responses
1,726 views
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by RTK45
03-26-2012, 12:13 PM
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Started by pravee1216, 03-20-2012, 08:36 AM
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5 responses
4,915 views
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by jflowers
03-26-2012, 08:19 AM
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Started by RTK45, 03-26-2012, 02:09 AM
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1 response
2,337 views
0 reactions
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by NicoBxl
03-26-2012, 06:47 AM
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Started by Phantom123, 03-26-2012, 06:47 AM
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0 responses
5,624 views
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by Phantom123
03-26-2012, 06:47 AM
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Started by Protaeus, 10-04-2010, 10:34 AM
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2 responses
4,780 views
0 reactions
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by Kasycas
03-26-2012, 05:13 AM
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Started by Abhishek, 03-24-2012, 01:27 AM
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5 responses
2,891 views
0 reactions
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by severin
03-26-2012, 04:51 AM
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Started by 54016565, 03-23-2012, 08:43 AM
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1 response
3,407 views
0 reactions
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Last Post
by BaCh
03-26-2012, 03:08 AM
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Started by louis7781x, 03-26-2012, 02:00 AM
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0 responses
1,273 views
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Last Post
by louis7781x
03-26-2012, 02:00 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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0 responses
9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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