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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,622 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,217 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Orr Shomroni, 02-10-2012, 01:54 AM
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0 responses
1,372 views
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by Orr Shomroni
02-10-2012, 01:54 AM
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Started by zmartine, 02-07-2012, 07:51 AM
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8 responses
6,931 views
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by jkbonfield
02-10-2012, 01:31 AM
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Started by chadn737, 02-09-2012, 09:55 PM
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2,388 views
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by chadn737
02-09-2012, 09:55 PM
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Started by ashuchawla, 02-09-2012, 10:06 AM
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5 responses
2,887 views
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by nickloman
02-09-2012, 11:12 AM
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Started by kgulukota, 02-07-2012, 08:39 AM
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3 responses
2,256 views
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by kgulukota
02-09-2012, 10:20 AM
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Started by droog_22, 02-09-2012, 08:53 AM
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0 responses
2,123 views
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by droog_22
02-09-2012, 08:53 AM
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Started by nwalwort, 02-07-2012, 08:26 PM
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6 responses
2,581 views
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by nwalwort
02-09-2012, 08:47 AM
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Started by shawpa, 02-09-2012, 04:25 AM
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6 responses
2,634 views
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by dpryan
02-09-2012, 07:27 AM
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Started by pettervikman, 11-11-2011, 03:12 AM
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23 responses
15,665 views
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by Tirtha
02-09-2012, 05:45 AM
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Started by vanbug, 02-08-2012, 05:37 AM
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7 responses
3,532 views
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Last Post
by vanbug
02-09-2012, 01:47 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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