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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,366 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,267 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by pmcqt, 11-29-2011, 06:48 AM
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0 responses
2,738 views
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by pmcqt
11-29-2011, 06:48 AM
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Started by dgtnk, 11-28-2011, 06:03 PM
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1 response
3,637 views
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by dgtnk
11-29-2011, 02:57 AM
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Started by dariober, 05-17-2011, 04:56 AM
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19 responses
16,323 views
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by cjp
11-29-2011, 02:51 AM
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Started by fongchun, 11-04-2011, 10:43 AM
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6 responses
3,889 views
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by airtime
11-29-2011, 01:04 AM
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Started by gprakhar, 11-23-2011, 02:22 PM
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2 responses
2,943 views
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by gprakhar
11-28-2011, 11:39 PM
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Started by royalchan, 11-22-2011, 11:59 AM
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2 responses
2,295 views
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by royalchan
11-28-2011, 10:40 PM
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Started by ians, 11-28-2011, 12:42 PM
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0 responses
2,105 views
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by ians
11-28-2011, 12:42 PM
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Started by feng, 11-28-2011, 09:03 AM
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2 responses
4,324 views
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by feng
11-28-2011, 12:33 PM
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Qiime
by nguyendofx
Started by nguyendofx, 11-28-2011, 10:47 AM
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2,051 views
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by nguyendofx
11-28-2011, 10:47 AM
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Started by history_of_robots, 07-05-2011, 04:49 PM
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1 response
3,221 views
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Last Post
by vsravi
11-28-2011, 08:56 AM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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