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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,620 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,198 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by NanYu, 06-06-2011, 02:55 PM
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1 response
1,359 views
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by nilshomer
06-06-2011, 03:54 PM
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Started by fbelzile62, 06-02-2011, 08:11 AM
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3 responses
3,545 views
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by robs
06-06-2011, 01:59 PM
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Started by clariet, 06-06-2011, 01:30 PM
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0 responses
2,315 views
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by clariet
06-06-2011, 01:30 PM
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Started by ltyang, 06-03-2011, 09:50 AM
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2 responses
1,851 views
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by Chipper
06-06-2011, 01:21 PM
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Started by Nix, 09-24-2010, 02:34 PM
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4 responses
3,596 views
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by oiiio
06-06-2011, 12:46 PM
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Started by ElMichael, 06-06-2011, 06:52 AM
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1 response
1,981 views
0 reactions
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by sklages
06-06-2011, 12:22 PM
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Started by HMorrison, 06-06-2011, 10:02 AM
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0 responses
1,670 views
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by HMorrison
06-06-2011, 10:02 AM
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Started by newbietonextgen, 05-07-2011, 06:28 PM
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3 responses
3,122 views
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by prisnirath
06-06-2011, 07:34 AM
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Started by MatthewVC, 06-02-2011, 02:15 PM
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2 responses
3,809 views
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by MatthewVC
06-06-2011, 07:29 AM
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Started by akolman, 06-04-2011, 09:43 PM
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8 responses
5,541 views
0 reactions
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Last Post
by akolman
06-06-2011, 07:26 AM
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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7 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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