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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,462 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,594 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by bogdan, 01-20-2011, 10:24 PM
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1,910 views
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by bogdan
01-20-2011, 10:24 PM
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Started by doc2r, 01-18-2011, 03:35 PM
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3 responses
1,948 views
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by biznatch
01-20-2011, 10:14 AM
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Started by derobins, 01-19-2011, 03:23 PM
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1 response
2,217 views
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by maubp
01-20-2011, 10:06 AM
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Started by calexand, 01-20-2011, 08:42 AM
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1 response
3,019 views
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by calexand
01-20-2011, 09:14 AM
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Started by SongLi, 01-19-2011, 10:31 AM
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5 responses
3,005 views
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by SongLi
01-20-2011, 08:39 AM
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Started by gfmgfm, 01-19-2011, 01:08 PM
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2 responses
2,556 views
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by lh3
01-20-2011, 06:49 AM
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Started by dariober, 01-19-2011, 02:02 AM
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4 responses
3,311 views
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by pmiguel
01-20-2011, 05:43 AM
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Started by FelipeAd, 01-07-2011, 04:42 AM
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29 responses
8,372 views
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by Jeremy
01-19-2011, 09:15 PM
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Started by AndrewCarpenter, 07-19-2010, 05:30 AM
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3 responses
4,398 views
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by zun
01-19-2011, 07:16 PM
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Started by hyj004, 01-19-2011, 02:54 PM
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0 responses
1,868 views
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by hyj004
01-19-2011, 02:54 PM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Today, 10:26 AM
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by SEQadmin2
Today, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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