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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,682 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,961 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by nimmi, 01-12-2011, 12:59 PM
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0 responses
2,125 views
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by nimmi
01-12-2011, 12:59 PM
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Started by skblazer, 01-12-2011, 12:59 PM
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0 responses
3,083 views
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by skblazer
01-12-2011, 12:59 PM
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Started by frymor, 01-12-2011, 04:03 AM
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2 responses
2,190 views
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by csoong
01-12-2011, 12:45 PM
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Started by gfmgfm, 01-12-2011, 11:20 AM
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2,000 views
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by gfmgfm
01-12-2011, 11:20 AM
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Started by madsaan, 01-11-2011, 06:46 AM
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2 responses
3,206 views
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by madsaan
01-12-2011, 09:55 AM
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Started by Airwalker810, 01-11-2011, 01:24 PM
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4 responses
2,862 views
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by Airwalker810
01-12-2011, 09:20 AM
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Started by sabrina7, 03-19-2010, 01:51 AM
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11 responses
8,462 views
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by nilshomer
01-12-2011, 08:52 AM
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Started by FelipeAd, 01-12-2011, 06:57 AM
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3 responses
2,257 views
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by FelipeAd
01-12-2011, 08:13 AM
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Started by dschika, 01-11-2011, 05:58 AM
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3 responses
5,654 views
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by kmcarr
01-12-2011, 06:53 AM
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Started by JackieBadger, 01-12-2011, 06:26 AM
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0 responses
1,582 views
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by JackieBadger
01-12-2011, 06:26 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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11 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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30 views
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by SEQadmin2
08-06-2026, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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48 views
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by SEQadmin2
08-03-2026, 10:13 AM
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