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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,619 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,185 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by newbietonextgen, 12-09-2010, 02:26 PM
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5 responses
3,000 views
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by vgrubor
12-10-2010, 02:42 PM
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Started by rdeborja, 12-09-2010, 02:26 PM
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1 response
1,359 views
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by drio
12-10-2010, 09:35 AM
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Started by harrb, 12-10-2010, 07:40 AM
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0 responses
1,866 views
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by harrb
12-10-2010, 07:40 AM
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Started by harrb, 12-09-2010, 11:36 AM
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2 responses
3,492 views
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by harrb
12-10-2010, 07:37 AM
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Started by dagarfield, 11-09-2010, 04:18 PM
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3 responses
2,365 views
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by dagarfield
12-10-2010, 06:58 AM
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Started by Protaeus, 12-09-2010, 03:38 PM
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2 responses
5,046 views
0 reactions
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by epigen
12-10-2010, 03:31 AM
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Started by semna, 12-10-2010, 02:59 AM
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0 responses
1,718 views
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by semna
12-10-2010, 02:59 AM
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Started by Chandana, 12-10-2010, 12:26 AM
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0 responses
1,788 views
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by Chandana
12-10-2010, 12:26 AM
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Started by mindlessbrain, 12-09-2010, 09:19 AM
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2 responses
2,383 views
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by sklages
12-09-2010, 11:47 PM
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Started by genelab, 12-09-2010, 11:24 PM
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0 responses
2,207 views
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by genelab
12-09-2010, 11:24 PM
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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6 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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11 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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