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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,633 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,323 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by zcrself, 03-16-2010, 05:32 PM
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0 responses
1,550 views
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by zcrself
03-16-2010, 05:32 PM
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Started by telos, 03-16-2010, 10:39 AM
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0 responses
1,843 views
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by telos
03-16-2010, 10:39 AM
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BWA question
by jyli
Started by jyli, 03-16-2010, 06:13 AM
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0 responses
1,686 views
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by jyli
03-16-2010, 06:13 AM
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Started by thinkRNA, 02-10-2010, 05:41 PM
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5 responses
2,374 views
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Started by damiankao, 03-16-2010, 04:28 AM
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0 responses
1,986 views
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by damiankao
03-16-2010, 04:28 AM
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Started by Nicolas902, 02-24-2010, 04:42 AM
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5 responses
3,597 views
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by cur
03-16-2010, 03:00 AM
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Started by 454andSolid, 03-16-2010, 02:22 AM
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0 responses
2,412 views
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by 454andSolid
03-16-2010, 02:22 AM
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Started by littlebio, 03-15-2010, 11:41 PM
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5 responses
5,563 views
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by littlebio
03-16-2010, 12:36 AM
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Started by Gangcai, 03-12-2010, 11:23 PM
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2 responses
2,499 views
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by Gangcai
03-16-2010, 12:05 AM
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Started by johnsequence, 03-09-2010, 08:08 AM
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9 responses
4,484 views
0 reactions
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Last Post
by bioinfosm
03-15-2010, 01:36 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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18 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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15 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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14 views
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by SEQadmin2
07-23-2026, 11:41 AM
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