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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,373 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,303 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by SDPA_Pet, 04-06-2017, 04:03 PM
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3 responses
1,616 views
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by gringer
04-07-2017, 04:17 AM
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Started by jmah, 03-31-2017, 09:43 AM
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1 response
2,739 views
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by jmah
04-06-2017, 04:40 PM
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Started by renuka22, 04-02-2017, 05:32 PM
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4 responses
3,224 views
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by renuka22
04-04-2017, 11:22 AM
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Started by JoeT, 04-04-2017, 10:48 AM
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0 responses
2,831 views
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by JoeT
04-04-2017, 10:48 AM
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Started by chammer, 04-03-2017, 06:43 AM
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4 responses
3,882 views
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by chammer
04-04-2017, 10:30 AM
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Started by Anastaziel, 04-04-2017, 06:37 AM
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0 responses
4,209 views
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by Anastaziel
04-04-2017, 06:37 AM
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where are my reads going: millions of fragments that uniquely aligned to the genes
by rammohanshukla
Started by rammohanshukla, 04-03-2017, 04:43 PM
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3 responses
1,638 views
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Last Post
by mastal
04-04-2017, 06:31 AM
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Started by mominchen, 04-03-2017, 12:56 PM
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4 responses
2,292 views
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by mominchen
04-04-2017, 02:21 AM
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Started by sadiexiaoyu, 04-03-2017, 02:46 AM
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0 responses
1,276 views
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by sadiexiaoyu
04-03-2017, 02:46 AM
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Started by vklearn, 03-31-2017, 12:13 AM
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1 response
2,922 views
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Last Post
by wdecoster
03-31-2017, 02:03 AM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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