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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,532 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,875 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by FlorianT, 03-28-2017, 07:10 AM
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3,637 views
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by FlorianT
03-28-2017, 07:10 AM
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Started by ecSeq Bioinformatics, 03-28-2017, 04:11 AM
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3,699 views
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Started by GenoMax, 03-19-2017, 05:08 PM
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12 responses
4,598 views
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by jkbonfield
03-28-2017, 01:01 AM
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Started by SeqTroubles, 03-24-2017, 02:33 AM
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2 responses
4,254 views
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by SeqTroubles
03-27-2017, 11:40 PM
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MutScan: detect and visualize target mutations by just scanning FastQ, 50X faster tha
by [email protected]
Started by [email protected], 03-27-2017, 05:27 PM
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0 responses
1,591 views
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Started by paumarc, 04-17-2015, 12:51 AM
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14 responses
9,975 views
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by nikooki2016
03-27-2017, 12:01 PM
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Started by adrian, 03-22-2017, 07:41 PM
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1 response
2,364 views
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by 2nelly
03-27-2017, 02:05 AM
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Started by JornBR, 03-24-2017, 07:40 AM
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3 responses
1,480 views
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by gringer
03-26-2017, 03:32 PM
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Started by capricy, 03-24-2017, 11:58 AM
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1 response
1,581 views
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by GenoMax
03-26-2017, 03:22 AM
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Started by splaisan, 03-25-2017, 06:20 AM
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0 responses
3,779 views
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by splaisan
03-25-2017, 06:20 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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25 views
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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35 views
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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