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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,654 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,413 views
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by ECO
12-25-2009, 06:45 PM
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Started by Letia, 07-29-2015, 12:29 AM
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1 response
1,100 views
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by hoytpr
09-04-2015, 07:05 AM
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Started by sbdk82, 07-15-2014, 03:59 PM
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5 responses
4,890 views
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by pengchy
09-04-2015, 06:32 AM
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Started by Irina Pulyakhina, 09-04-2015, 06:15 AM
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1,276 views
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Started by Neberir, 02-27-2015, 07:28 AM
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4 responses
2,081 views
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by znasim09
09-04-2015, 03:44 AM
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Started by intregen, 09-03-2015, 12:48 PM
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1 response
2,885 views
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Started by sam_kh918, 09-03-2015, 01:22 PM
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0 responses
985 views
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by sam_kh918
09-03-2015, 01:22 PM
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Started by ARSoares, 09-03-2015, 09:39 AM
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0 responses
1,239 views
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by ARSoares
09-03-2015, 09:39 AM
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Started by MeganS, 04-23-2013, 10:17 PM
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4 responses
5,210 views
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Started by maki.dur, 09-03-2015, 06:44 AM
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1,258 views
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by maki.dur
09-03-2015, 06:44 AM
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Started by Akis, 09-02-2015, 06:44 AM
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5 responses
1,973 views
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by Akis
09-03-2015, 05:07 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 10:13 AM
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10 views
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by SEQadmin2
Today, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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23 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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