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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,350 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,163 views
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by ECO
12-25-2009, 06:45 PM
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Started by BioFalcon, 12-15-2014, 12:41 PM
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1,379 views
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by BioFalcon
12-15-2014, 12:41 PM
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Started by Nino, 12-15-2014, 12:37 PM
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1,537 views
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by Nino
12-15-2014, 12:37 PM
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Started by jazz710, 12-15-2014, 10:43 AM
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3,173 views
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by jazz710
12-15-2014, 10:43 AM
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Started by gene_x, 12-11-2014, 09:05 PM
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8 responses
13,527 views
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by gene_x
12-15-2014, 09:22 AM
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Started by sunkid, 11-14-2014, 10:37 AM
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11 responses
2,353 views
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by aggp11
12-15-2014, 08:34 AM
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Started by LilianK, 12-15-2014, 07:48 AM
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1,022 views
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by LilianK
12-15-2014, 07:48 AM
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Started by Zhan yueping, 12-14-2014, 04:45 AM
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3 responses
1,872 views
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by Zhan yueping
12-15-2014, 04:17 AM
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Started by polmed, 12-14-2014, 08:52 PM
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1 response
1,938 views
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by GenoMax
12-15-2014, 04:13 AM
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Started by Bara'a Al-Hammad, 12-11-2014, 09:48 AM
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8 responses
3,195 views
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Started by ctsa, 06-12-2012, 08:18 AM
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15 responses
10,679 views
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by Jane M
12-15-2014, 02:38 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Yesterday, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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