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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,689 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,070 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by swNGS, 04-27-2012, 01:09 PM
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10 responses
7,388 views
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by brdido
04-30-2014, 09:13 AM
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Started by semna, 02-23-2011, 02:46 AM
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9 responses
2,544 views
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by anikng
04-30-2014, 05:00 AM
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Started by k_a_r_o_l, 04-30-2014, 04:43 AM
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0 responses
1,912 views
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by k_a_r_o_l
04-30-2014, 04:43 AM
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Started by henry, 11-26-2009, 02:55 AM
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7 responses
8,872 views
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by mastal
04-30-2014, 03:52 AM
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Started by RocheKermit, 04-30-2014, 01:03 AM
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0 responses
1,547 views
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by RocheKermit
04-30-2014, 01:03 AM
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Started by ecSeq Bioinformatics, 04-23-2014, 01:27 AM
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1 response
2,392 views
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Started by Wei-HD, 01-23-2010, 02:13 PM
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21 responses
12,425 views
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by archi
04-29-2014, 11:33 PM
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Started by greigite, 06-01-2009, 10:31 AM
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8 responses
4,904 views
0 reactions
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by sklages
04-29-2014, 11:04 PM
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Started by a_mt, 04-28-2014, 10:25 PM
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2 responses
6,857 views
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by a_mt
04-29-2014, 10:46 PM
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Started by rpbaptista, 05-05-2013, 07:37 PM
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5 responses
3,898 views
0 reactions
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by tw7649116
04-29-2014, 10:44 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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0 responses
19 views
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by SEQadmin2
08-13-2026, 12:22 PM
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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0 responses
16 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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0 responses
32 views
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by SEQadmin2
08-06-2026, 07:41 AM
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