Hi all,
I am looking for a fast executable that can join read pairs into single pseudo-reads so that I can apply FastQC on the joined sequences instead of performing two independent fastQC runs.
I wonder why fastQC does not offer that option out of the box!!
I could make my own simple perl/python/java code (using chat-gpt) but am sure there is a more performant compiled version somewhere (my best score is ~6sec / million PE150).
Note: the reads are considered non-overlapping, although many likely are, because I want to get the quality check of the full raw read pair.
I do not intend to merge them for further analysis as they would not correspond to real sequences anymore (plenty of tools for merging exist but will force merging).
Any advice is welcome
Cordially
Stephane
-
Kheloyaar: The Complete Guide to Kheloyaar Loginand Kheloyaar ID
The online gaming industry has transformed the way people enjoy digital entertainment. As technology continues to improve, players are looking for platforms that offer convenience, security, and a seamless user experience. Kheloyaarhas gained attention among users who value an easy-to-use platform, quick account access, and a simple registration process.
Whether you're exploring Kheloyaar for the first time or want to understand...Today, 09:27 PM -
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...Today, 11:10 AM -
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...Yesterday, 05:17 AM