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preliminary studies have shown that the TF that i am interested in can bind to DNA transposable elements . the problem is; when mapping the reads to the human genome, what is the certainty that it will map to the right site. is it possible that i will get multiple hits?Last edited by eze; 08-19-2009, 08:13 AM. -
chip-seq and repetitive elements
hello everyone,
i am a new post-doc at Yale university, from Nigeria an received my PhD in Biomedical Science
i have a technical question i was hoping i could get some assistance with.
I am interested in starting a Chip-Seq study to determine transcription factor binding sites in differentiated Human Endometrial Stromal cells. I am interested in binding sites at repetitive elements and was wondering about the certainty of mapping the binding sites to specific regions of the human genome.Last edited by eze; 08-18-2009, 09:01 AM.
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The first FDA-approved CRISPR-based therapy marked the transition of therapeutic gene editing from a dream to reality1. CRISPR technologies have streamlined gene editing, and CRISPR screens have become an important approach for identifying genes involved in disease processes2. This technique introduces targeted mutations across numerous genes, enabling large-scale identification of gene functions, interactions, and pathways3. Identifying the full range...08-27-2024, 04:44 AM
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